The Pulpit Commentary - Isaiah 51:22
The Lord … that pleadeth the cause of his people (comp. Jeremiah 50:34 , which contains an allusion to this passage). As his people have a relentless adversary, who accuses them continually, and pleads against them ( Revelation 12:10 ), so it is needful that they should have an untiring advocate. God himself is this Advocate. The dregs of the cup (see the comment on Isaiah 51:17 , ad fin. ) . read more
The Pulpit Commentary - Isaiah 51:21
Drunken, but not with wine (comp. Isaiah 29:9 ; and see above, Isaiah 29:17 , which shows that the appearance of drunkenness had been produced by Jerusalem drinking the cup of God's wrath). read more