Calandio or Calendio ( Καλανδίων ), succeeded Stephen II. as bp. of Antioch, a.d. 481. He owed his promotion to the episcopate to the emperor Zeno and Acacius, bp. of Constantinople; but the exact circumstances of his appointment are uncertain. There is a large body of evidence (not, however, to be admitted without grave question) that Calandio's election was of the same uncanonical character as that of his predecessor in the see [See Stephen II..]; and that being at Constantinople on business connected with the church of Antioch at the time of the vacancy of the see, he was chosen bishop, and ordained by Acacius; but the letter of pope Simplicius to Acacius, dated July 15, a.d. 482, conveying his sanction of Calandio's election (Labbe, Conc. iv. 1035), suggests a possible confusion between the election of Calandio and of Stephen II.
Calandio commenced his episcopate by excommunicating his theological opponents. He refused communion with all who declined to anathematize Peter the Fuller, Timothy the Weasel, and the Encyclic of Basiliscus condemning the decisions of the council of Chalcedon (Evagr. H. E. iii. 10; Niceph. H. E. xv. 28). He is reported to have endeavoured to counteract the Monophysite bias given to the Trisagion by Peter the Fuller in the addition of the words ὁ σταυρωθεὶς δἰ᾿ ἡμᾶς , by prefixing the clause Χριστὲ Βασιλεῦ (Theod. Lector. p. 556 B.) Calandio translated the remains of Eustathius, the banished bp. of Antioch, with the permission of Zeno, from Philippi in Macedonia, where he had died, to his own cityâ€”a tardy recognition of the falsehood of the charges against Eustathius, which had the happy result of reuniting to the church the remains of the party that still called itself by his name (Theod. Lector. p. 577; Theophanes, p. 114). Calandio fell into disfavour and was banished by the Emperor Zeno, at the instigation of Acacius, to the African Oasis, a.d. 485, where, probably, he died. The charge against him was that of having erased from the diptychs the name of Zeno, as the author of the Henoticon; and of having favoured Illus and Leontius in their rebellion, a.d. 484. But the real cause of his deposition was the theological animosity of Acacius, whom he had offended by writing a letter to Zeno accusing Peter Mongus of adultery, and of having anathematized the decrees of the council of Chalcedon (Evagr. H. E. ii. 16; Liberatus Diaconus, Breviar. c. xviii.; Gelasius, Ep. xiii. ad Dardan. Episc.; Labbe, iv. 1208â€“1209, xv. ad Episc. Orient. ib. 1217). On his deposition, the victorious Peter the Fuller was recalled to occupy the see of Antioch.