Mark 3:31

And there come his mother and his brethren; and, standing without, they sent unto him, calling him.

As noted under Mark 3:21, this terminology applied to Jesus' immediate family makes it impossible to construe "friends" in that verse as a reference to the same persons. Turlington said:

This passage must not be used as evidence that Jesus' mother opposed his mission ... That Mary was among the "friends" of Mark 3:21 is an unlikely and unnecessary conclusion.[11]

It is true that Jesus' brothers did not believe in him, even as late as October prior to the Passion in April of the following year (John 7:5), but there is no evidence that the mother and brethren said, "He is crazy" and tried to get him locked up, as indicated in some of the perverted paraphrases marketed under misleading titles as "translations."

And his brethren ... The most logical way to understand this reference to Jesus' brothers is that the persons meant were his literal brothers, sons of Joseph and Mary after Jesus was born. This view is harmonious with all the Scriptures say of the blessed Mary, whose virginity PRIOR TO THE BIRTH OF JESUS is clearly stated, but whose so-called perpetual virginity is nothing but superstition. See Matthew 13:55 for names of his four brothers.

Sent to him and called him ... means only that they asked to see and talk with Jesus.