Mark 6:2

And when the sabbath was come, he began to teach in the synagogue: and many hearing him were astonished, saying, Whence hath this man these things? and, What is the wisdom that is given unto this man, and what mean such mighty works wrought by his hands?

This man ... as sneeringly repeated by the villagers was derogatory. "There is a contemptuous tone about the expression."[2] The citizens of the Lord's home town despised him because he was one of themselves. Having no conception of their own value as human beings, they made their own guilty unworthiness the basis of rejecting the Lord. The light of all ages shone in their dark streets, but they were blind to it. (See full discussion of the phenomenon of Nazareth's unbelief in my Commentary on Matthew, pp. 207-210).

This was the second rejection of Jesus at Nazareth, the first being recorded in Luke 4:15ff. Matthew 13:54-58 is parallel to this account of the second rejection.