John 16:3

And these things will they do, because they have not known the Father, nor me.

The world's hatred of truth derives primarily from ignorance; but it is not an excusable ignorance.

(The world's ignorance) is rather a part of their sin, but a part which accounts for the rest. That when light came into the world, they loved darkness rather than light (John 3:19), was in a high degree sinful.[5]

Lipscomb said of this:

It is but another way of saying that there is an eternal and uncompromising enmity on the part of those who know not God and his Son Jesus Christ against those who walk with God and believe on the Lord.[6]

[5] Alvah Hovey, op. cit., p. 311.

[6] David Lipscomb, A Commentary on the Gospel of John (Nashville: Gospel Advocate Company, 1960), p. 250.