1 Timothy 2:5

For there is one God, one mediator also between God and men, himself man, Christ Jesus,

As David Lipscomb noted, the reference to Jesus Christ as a man is in the present tense, despite the fact of this having been written after the ascension of Christ, indicating that our Lord did not cease being a man when he rose from the dead and ascended to the right hand of God. In like manner, he did not cease being God when he descended for the purpose of the Incarnation.

One God ... With great difficulty, the Hebrew people were finally taught the truth of monotheism; but, in spite of many lapses, they came in time, following the Babylonian captivity, to accept the principle completely. However, they failed, even then, to appreciate the truth that God is the God of all people, not of Israel alone; and there is always the tendency for people to think of God as THEIRS and not the God of all. This paragraph is charged with the truth that God is God of all. Lenski rejected the American Standard Version translation of this verse, affirming the meaning actually to be:

One (is) God, not two or more. One also (is) Mediator for God and men, not several. Nor should these two facts be separated, for they have been joined in 1 Timothy 2:3 where "our Saviour God" joins them; and they are again joined here. This Mediator is Mediator "for this one," namely, for God and men.[12]

One mediator ... There are exactly as many mediators as there are God, namely, only one; and here is the end of any alleged legitimacy for invoking saints, or even the Virgin Mary, in one's petitions to God.