Luke 22:22

And truly the son of man goeth ,.... That is, dies, which is going the way of all the earth, Joshua 23:14

as it was determined ; in the counsels and purposes of God, and agreed to by Christ in the covenant of grace; see Acts 2:23 the death of Christ, the manner of it, and the means by which it was brought about, were all predetermined by God; yet this did not, in the least, excuse the sin of those concerned in it, nor exempt them from punishment:

but woe unto that man by whom he is betrayed ; who not only came to an untimely end, and died an infamous death by his own hands, but went to his own place, the place of everlasting torments allotted him: wherefore in Matthew 26:24 it is added, "it had been good for that man if he had not been born"; See Gill on Matthew 26:24 .