Deuteronomy 28:59

Then the Lord will make thy plagues wonderful ,.... Visible, remarkable, distinguishable, and astonishing to all that see them:

and the plagues of thy seed ; for they were to continue, as they have done, With their posterity, age after age:

even great plagues, and of long continuance ; great as to quality and quantity, and firm, sure, lasting, and durable; the word used is rendered "sure" in Isaiah 55:3 ; sure by prophecy and in the event; and which when inflicted remained, as they have 1700 years; all which might be believed as certain, or what would certainly come to pass, and be depended on:

and sore sicknesses, and of long continuance ; besides those diseases mentioned Deuteronomy 28:27 ; or however others including them.