(1):

(n.) One who, or that which, bothers; state of perplexity or annoyance; embarrassment; worry; disturbance; petty trouble; as, to be in a bother.

(2):

(v. t.) To annoy; to trouble; to worry; to perplex. See Pother.

(3):

(v. i.) To feel care or anxiety; to make or take trouble; to be troublesome.