(1):

(n.) A medicine or application that has the quality of easing pain or protecting from the action of irritants.

(2):

(n.) A mild purgative; a laxative.

(3):

(n.) That which softens or mitigates; that which tends to allay passion, excitement, or pain; a palliative.

(4):

(a.) Having the quality of softening or mitigating, as pain or acrimony; assuasive; emollient.