(1):

(a.) Very miserable; sunk in, or accompanied by, deep affliction or distress, as from want, anxiety, or grief; calamitous; woeful; very afflicting.

(2):

(a.) Worthless; paltry; very poor or mean; miserable; as, a wretched poem; a wretched cabin.

(3):

(a.) Hatefully contemptible; despicable; wicked.