Gregory of Nyssa was a Christian bishop and saint. He was a younger brother of Basil the Great and a good friend of Gregory Nazianzus. His significance has long been recognized in the Eastern Orthodox, Oriental Orthodox, and Roman Catholic branches of Christianity.

Gregory along with his brother Basil of Caesarea and Gregory of Nazianzus are known as the Cappadocian Fathers. They attempted to establish Christian philosophy as superior to Greek philosophy.