Zechariah 14:13

"And it shall come to pass in that day, that a great tumult from Jehovah shall be among them; and they shall lay hold every one on the hand of his neighbor, and his hand shall rise up against the hand of his neighbor."

Both the previous verse and this one are descriptive of the ultimate and final apostasy of the whole human race which shall issue in the eternal judgment, being preceded by a time of anarchy, chaos, and universal destruction, in which the "cities of the nations" shall fall. (Revelation 16:19). Revelation 18 is a further elaboration of the same situation.

This verse describes what the "plague" of Zechariah 14:12 actually is. It is the ultimate appearance of the kind of society that inevitably results when God's will is almost totally rejected on earth. When the rebellious rulers of earth's kingdoms shall succeed in the near-destruction of every vestige of religion from the earth (even the accommodative religion characteristic of the apostasy), they shall suddenly discover what such a world really is. Then will come the wailing of the kings and the mighty men who sorrow and grieve for all of the wretched disasters that have fallen upon them. That is when they will cast dust upon their heads and lament for that which they themselves had effectively destroyed. (Revelation 18). As the prophet said a few lines earlier, "In the evening time, there shall be light!" God will finally permit this rebellious humanity gone berserk against the will of God, and steering a collision course with disaster, to discover just what serving the devil actually means.