Isaiah 24:4

"The earth mourneth and fadeth away, the world languisheth and fadeth away, the lofty people of the earth do languish. The earth also is polluted under the inhabitants thereof; because they have transgressed the laws, violated the statutes, broken the everlasting covenant. Therefore hath the curse devoured the earth, and they that dwell therein are found guilty: therefore, the inhabitants of the earth are burned, and few men left."

Isaiah 24:5 here explains the reason why such terrible things are in store for the earth and its inhabitants. The inhabitants themselves are declared "guilty." They have: (1) transgressed God's laws, and (2) they are specifically guilty of breaking the everlasting covenant of Genesis 9:16.

On this latter violation, Peake has this:

"For the world's inhabitants have broken the covenant made with Noah, in which bloodshed was forbidden (Genesis 9:6,16). On bloodshed, the great empires have been founded, and they shall perish in the blood they have spilt."[6]

We believe Peake's comment here is accurate; and we wish to add that the most terrible thing visible in the societies of mankind this very day is the utter disregard of this Divine Commandment in Genesis 9:6. It not only condemns and forbids bloodshed; but it also commands every society of mankind to "Put to death all murderers." "Whoso sheddeth man's blood, by man (society) shall his blood be shed: for in the image of God made he man." This heavenly order to execute murderers is not an option given to human societies, but an order. Any human society stupid enough to ignore that heavenly commandment will soon find itself devastated by all kinds of violence, murder, and crime.

The mention of the inhabitants of the earth being burned (Isaiah 24:6), according to Barnes, "is evidently figurative";[7] but we do not accept that view. An apostle of Jesus told us that: (1) the world that then was overflowed with water and perished, and (2) the same world is now stored up for fire against the day of judgment and destruction of ungodly men (2 Peter 3:1-10). There is no hint whatever that the fire spoken of by Peter was otherwise than literal. Also, Peter mentioned the flood in the same breath with this picture of the final judgment; and we have exactly the same thing here. Isaiah mentioned "the windows on high" (Isaiah 24:18) and the burning of the inhabitants of the earth here.

From Genesis to the end of the Bible, "God's cursing the ground for Adam's sake" is repeatedly evident. As the wickedness of mankind grows worse and worse, which is the normal growth-cycle of wickedness, it appears that the earth itself will become more and more hostile to the desires of men.