Daniel 11:6

In the South, Ptolemy I eventually died in 285 B.C., leaving his throne to his son, Ptolemy II Philadelphus (285-246 B.C.).

In the North, Seleucus I was the victim of an assassin in 281 B.C., and his son, Antiochus I Soter (281-262 B.C.), began ruling in his place. Antiochus I died in 262 B.C. and left his son, Antiochus II, in power.

Ptolemy II of Egypt and Antiochus II of Syria were contemporaries. They were also bitter enemies. However, they finally made an alliance about 250 B.C., which they sealed with the marriage of Ptolemy II’s daughter, Berenice, to Antiochus II. When Ptolemy II died in 246 B.C., Antiochus II took back his first wife, Laodice, whom Antiochus had divorced to marry Berenice. Laodice is the woman for whom the town of Laodicea in Asia Minor was named (Revelation 3:14; et al.). Similarly, the towns of Antioch, in Syria and in Asia Minor, received their names from Antiochus. Antioch of Syria was the capital of Syria during the Selucid dynasty. To gain revenge, Laodice had Berenice and her infant son by Antiochus murdered. Laodice also poisoned Antiochus and ruled in his place briefly. Her son, Seleucus II, then succeeded his father, Antiochus II, and ruled Syria beginning in 246 B.C. Berenice is the woman the angel referred to in this verse.

The NASB text says, "She [Berenice] will not retain her position of power [as queen of the North], but she will be given up [by her husband, Antiochus II], along with those who brought her in [perhaps the diplomats who arranged the marriage], and the one who sired her [her father, Ptolemy II], as well as he who supported her in those times [perhaps her supporting patron]."