Psalms 6:3-4

3, 4. My soul is… sore vexed Causes of mental, not less than of physical, trouble existed. Body and soul lay under the consuming force of the wrathful judgment. The word used to describe the effect upon his bones (“vexed, troubled”) is the same as defines the state of his soul. Delitzsch gives the sense of outward overthrow and inward consternation, the effect of fright, which disconcerts one, and of excitement, that deprives one of self-control.

How long Literally, till when? The interrogation is emphatic, and supposes the answer delayed, and the evil complained of such as cannot long be endured. See Exodus 10:3; Psalms 90:13; Isaiah 6:11. With this the perfect tense of the preceding verb (my soul has been vexed) agrees, as also the earnest return, (Psalms 6:4,) as if God had gone away from him. Compare 2 Corinthians 4:8: “Perplexed, but not in despair.”