Anatomist, born San Severino, Italy, 1520; died Rome, Italy, 1574. Appointed professor of anatomy at the Roman University, he availed himself of opportunities for original work and recorded his anatomical investigations in a series of plates with text attached, Clement XI defraying the expense of publishing those which had been deposited in the Vatican Library. With Vesalius and Columbus he established the modern science of anatomy, and it has been said that there is not a part of the body upon which he did not shed light. Among his most notable contributions are descriptions of the stirrup bone in the ear and the canal connecting ear and mouth, since called by his name, and the discovery of the circulatory function of what is known as the Eustachian valve near the opening of the inferior vena cava. Personal physician to Pope Sixtus V.