AMPHIPOLIS . A town in a part of Macedonia formerly reckoned to Thrace, on the river Strymon, about 3 miles from its mouth, where the harbour Eion was situated. It was a place of great strategic and mercantile importance. It underwent various vicissitudes, but retained its importance based on its abundant supplies of excellent wine, figs, oil, and wood, its silver and gold mines, its woollen fabrics. The Romans raised it to the rank of a free town and the chief town of the first district of the province Macedonia; through it the Via Egnatia passed. The verb in the Greek ( Acts 17:1 ) seems to indicate that St. Paul passed through it without preaching there.

A. Souter.