Francis Frangipane is a Christian evangelical minister and author. He is the founding pastor of River of Life Ministries in Cedar Rapids, Iowa, United States. In 2002, he also launched an international, online school called In Christ's Image Training (ICIT). This training lays a foundation of truth based on four principal themes: Christlikeness, humility, prayer and unity. ICIT has students in over seventy nations. Additionally, over the past decades, Frangipane has served on a number of other ministry boards. However, in recent years he has gradually resigned from these various boards. As of June 2009, he has also retired from his position as senior pastor of River of Life Ministries. In this more simplified life, Frangipane is devoting himself to prayer and the ministry of God's word.

Francis Frangipane has an active partnership with the Mission America Coalition, consisting of leaders from 81 denominations and over 400 ministries and networks. He is also a welcomed teacher in various Charismatic and Evangelical church settings, in both the black and white communities.