“But God has no natural relation to us, as the authors of the heresies will have it; neither on the supposition of His having made us of nothing, nor on that of having formed us from matter; since the former did not exist at all, and the latter is totally distinct from God, unless we shall dare to say that we are a part of Him, and of the same essence as God. And I know not how one, who knows God, can bear to hear this when he looks to our life, and sees in what evils we are involved. For thus it would turn out, which it were impiety to utter, that God sinned in [certain] portions, if the portions are parts of the whole and complementary of the whole; and if not complementary, neither can they be parts. But God being by nature rich in pity, in consequence of His own goodness, cares for us, though neither portions of Himself, nor by nature His children. And this is the greatest proof of the goodness of God: that such being our relation to Him, and being by nature wholly estranged, He nevertheless cares for us. For the affection in animals to their progeny is natural, and the friendship of kindred minds is the result of intimacy. But the mercy of God is rich toward us, who are in no respect related to Him; I say either in our essence or nature, or in the peculiar energy of our essence, but only in our being the work of His will.”
His parents were pagans, and Clement was a convert to Christianity. In the Protrepticus he displays an extensive knowledge of Greek mythology and mystery religions, which could only have arisen from the practise of his family's religion.
Having rejected paganism as a young man due to its perceived moral corruption, he travelled in Greece, Asia Minor, Palestine and Egypt. Clement's journeys were primarily a religious undertaking. In Greece, he encountered an Ionian theologian, who has been identified as Athenagoras of Athens; while in the east, he was taught by an Assyrian, sometimes identified with Tatian, and a Jew, who was possibly Theophilus of Caesarea.
In around 180, Clement reached Alexandria, where he met Pantaenus, who taught at the Catechetical School of Alexandria. Eusebius suggests that Pantaenus was the head of the school, but it is controversial whether the institutions of the school were formalized in this way before the time of Origen. Proponents of a formalized leadership and succession suggest that Clement succeeded Pantaenus as leader of the school, and was succeeded himself by Origen. Clement studied under Pantaenus, and was ordained to the priesthood by Pope Julian before 189. Otherwise, virtually nothing is known of Clement's life in Alexandria. He may have been married, a conjecture supported by his writings. Clement's diet is also unknown, but he said some things that look down upon eating flesh such as, "It is good...neither to eat flesh" and that even the fumes from cooked flesh "darken the soul"; however he said non-vegetarians aren't sinning except in certain circumstances such as those who eat flesh with "gluttony" and he was not opposed to all instances of eating meat.
During the Severian persecutions of 202–203, Clement left Alexandria. In 211, Alexander of Jerusalem wrote a letter commending him to the Church of Antioch, which may imply that Clement was living in in Cappadocia at that time. The date and location of his death are unknown.