“Plus tard, la sainte vigne produisit la grappe prophétique, c'est-à-dire la Verbe, dont le sang mêlé avec l'eau, suivant sa volonté, est le signe de ceux qui de l'erreur sont entrés dans le repos. Le sang entre en mélange avec le salut. Le sang du Seigneur est, de deux natures, l'un charnel qui nous rachète de la mort, l'autre spirituel, qui nous purifie. Boire le sang de Jésus, c'est participer à l'incorruptibilité du Seigneur. L'esprit est la force du Verbe, comme le sang est la force de la chair. Comme le vin se mêle à l'eau, l'esprit est mêlé avec l'homme. Ce mélange de l'un et de l'autre, je veux dire du Verbe et de la boisson, s'appelle Eucharistie, qui signifie de grâces; et ce sacrement sanctifie l'âme et le corps 95 de ceux qui y participent avec foi, lorsque la Volonté divine a mystiquement mélangé, par l'Esprit et le Verbe, ce divin breuvage qui représente l'homme. L'esprit, en effet, s'y mêle à l'âme, et le Verbe à la chair.”
His parents were pagans, and Clement was a convert to Christianity. In the Protrepticus he displays an extensive knowledge of Greek mythology and mystery religions, which could only have arisen from the practise of his family's religion.
Having rejected paganism as a young man due to its perceived moral corruption, he travelled in Greece, Asia Minor, Palestine and Egypt. Clement's journeys were primarily a religious undertaking. In Greece, he encountered an Ionian theologian, who has been identified as Athenagoras of Athens; while in the east, he was taught by an Assyrian, sometimes identified with Tatian, and a Jew, who was possibly Theophilus of Caesarea.
In around 180, Clement reached Alexandria, where he met Pantaenus, who taught at the Catechetical School of Alexandria. Eusebius suggests that Pantaenus was the head of the school, but it is controversial whether the institutions of the school were formalized in this way before the time of Origen. Proponents of a formalized leadership and succession suggest that Clement succeeded Pantaenus as leader of the school, and was succeeded himself by Origen. Clement studied under Pantaenus, and was ordained to the priesthood by Pope Julian before 189. Otherwise, virtually nothing is known of Clement's life in Alexandria. He may have been married, a conjecture supported by his writings. Clement's diet is also unknown, but he said some things that look down upon eating flesh such as, "It is good...neither to eat flesh" and that even the fumes from cooked flesh "darken the soul"; however he said non-vegetarians aren't sinning except in certain circumstances such as those who eat flesh with "gluttony" and he was not opposed to all instances of eating meat.
During the Severian persecutions of 202–203, Clement left Alexandria. In 211, Alexander of Jerusalem wrote a letter commending him to the Church of Antioch, which may imply that Clement was living in in Cappadocia at that time. The date and location of his death are unknown.