“Nevertheless, despite all superficial continuity, a remarkable change has come about within the last seventy-five years. The change is nothing less than the substitution of paganism for Christianity as the dominant view of life. Seventy-five years ago, Western civilization, despite inconsistencies, was still predominantly Christian; today it is predominantly pagan. (1923)”
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Born in Baltimore, Maryland, he came from a wealthy and well-educated background. He studied at John Hopkins University and then went to Princeton Theological Seminary, receiving an M.A. in philosophy. He studied in Germany and returned to teach New Testament at Princeton. He received his B.D. in 1905 and was ordained in the Presbyterian Church.
In 1929, he left Princeton Seminary when the institution capitulated to the liberal faction, and he, along with others, founded Westminster Theological Seminary. In 1934 he was censured by the Presbyterian Church for his actions in relation to the Presbyterian Board of Foreign Missions, the liberal bias of which he opposed. In 1935 he was defrocked by the Presbyterian Church over major doctrinal issues. Machen then established the Orthodox Presbyterian Church as a reaction to the liberalism of the Presbyterian hierarchy. He died at age 55, of pneumonia.