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Want to know what the Bible says about Sadness? Here are 122 Bible verses about Sadness from the Old and New Testaments of the Holy Bible, New International Version (NIV), sorted from the most relevant to the least relevant.

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Note: Always check the context of a verse; Click the "Read Full Chapter" button next to each verse to read more. The context of a verse might put a very different slant on what the verse seems to say.

Isaiah 53:4-6 NIV
4 Surely he took up our pain
    and bore our suffering,
yet we considered him punished by God,
    stricken by him, and afflicted.
5 But he was pierced for our transgressions,
    he was crushed for our iniquities;
the punishment that brought us peace was on him,
    and by his wounds we are healed.
6 We all, like sheep, have gone astray,
    each of us has turned to our own way;
and the Lord has laid on him
    the iniquity of us all.
12
Luke 11:1-4 NIV
11 One day Jesus was praying in a certain place. When he finished, one of his disciples said to him, “Lord, teach us to pray, just as John taught his disciples.”
2 He said to them, “When you pray, say:
“‘Father,
hallowed be your name,
your kingdom come.
3 Give us each day our daily bread.
4 Forgive us our sins,
    for we also forgive everyone who sins against us.
And lead us not into temptation. ’”
12
Hebrews 4:12 NIV
For the word of God is alive and active. Sharper than any double-edged sword, it penetrates even to dividing soul and spirit, joints and marrow; it judges the thoughts and attitudes of the heart.
12
John 16:28 NIV
I came from the Father and entered the world; now I am leaving the world and going back to the Father.”
11
Isaiah 26:3 NIV
You will keep in perfect peace
    those whose minds are steadfast,
    because they trust in you.
11
Matthew 24:36 NIV
“But about that day or hour no one knows, not even the angels in heaven, nor the Son, but only the Father.
11
1 Thessalonians 5:16-18 NIV
16 Rejoice always, 17 pray continually, 18 give thanks in all circumstances; for this is God’s will for you in Christ Jesus.
11
Isaiah 40:31 NIV
but those who hope in the Lord
    will renew their strength.
They will soar on wings like eagles;
    they will run and not grow weary,
    they will walk and not be faint.
11
John 1:1 NIV
In the beginning was the Word, and the Word was with God, and the Word was God.
10
Luke 6:12 NIV
One of those days Jesus went out to a mountainside to pray, and spent the night praying to God.
10

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